Anti-ATP6AP2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA003156.25	25 µl		-		7 - 10 business days*		300.00€
ATA-HPA003156.100	100 µl		-		7 - 10 business days*		421.00€

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Protein function: Multifunctional protein which functions as a renin, prorenin cellular receptor... more

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Product information "Anti-ATP6AP2"

Protein function: Multifunctional protein which functions as a renin, prorenin cellular receptor and is involved in the assembly of the lysosomal proton-transporting V-type ATPase (v-ATPase) and the acidification of the endo-lysosomal system (PubMed:12045255, PubMed:29127204, PubMed:30374053, PubMed:32276428). May mediate renin-dependent cellular responses by activating ERK1 and ERK2 (PubMed:12045255). By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, may also play a role in the renin-angiotensin system (RAS) (PubMed:12045255). Through its function in V-type ATPase (v- ATPase) assembly and acidification of the lysosome it regulates protein degradation and may control different signaling pathways important for proper brain development, synapse morphology and synaptic transmission. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 94% and to rat: 93%

Keywords:	Anti-HT028, Anti-ATP6IP2
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA003156

Properties

Application:	IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: NSLSRNNEVD LLFLSELQVL HDISSLLSRH KHLAKDHSPD LYSLELAGLD EIGKRYGEDS EQFRDASKIL VDALQKFADD MYSLYGGNAV VELVTVKSFD TSLIRKTRTI LEAKQAKNPA SPYNLAYKYN FEYSVVFN (ATA-APrEST74434)