Anti-ATP6AP1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG58326.100	100 µl		-	-	10 - 15 business days*		707.00€

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Protein function: Accessory subunit of the proton-transporting vacuolar (V)-ATPase protein pump,... more

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Product information "Anti-ATP6AP1"

Protein function: Accessory subunit of the proton-transporting vacuolar (V)-ATPase protein pump, which is required for luminal acidification of secretory vesicles. Guides the V-type ATPase into specialized subcellular compartments, such as neuroendocrine regulated secretory vesicles or the ruffled border of the osteoclast, thereby regulating its activity. Involved in membrane trafficking and Ca(2+)-dependent membrane fusion. May play a role in the assembly of the V-type ATPase complex. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633). [The UniProt Consortium]

Keywords:	Anti-ATP6IP1, Anti-ATP6AP1, Anti-Protein XAP-3, Anti-V-ATPase subunit S1, Anti-V-ATPase Ac45 subunit, Anti-V-ATPase S1 accessory protein, Anti-Vacuolar proton pump subunit S1, Anti-V-type proton ATPase subunit S1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG58326

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	Recombinant funsion protein corresponding to aa. 90-390 of Human ATP6AP1 (NP_001174.2)
MW:	52 kD
Format:	Affinity Purified