Anti-ATP2C1

Anti-ATP2C1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
029976.100 100 µl - -

3 - 19 business days*

477.00€
 
ATP2C1, also known as PMR1, it belongs to the family of P-type cation transport ATPases. This... more
Product information "Anti-ATP2C1"
ATP2C1, also known as PMR1, it belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium. The human homologue, ATP2C1 (also designated SPLA in rat), also regulates the transport of calcium in the Golgi complex and is related to other P-type ATPases family members, such as the sarco(endo)plasmic calcium ATPase (SERCA) and the plasma membrane calcium ATPase (PCMA). ATP2C1 is a transmembrane protein that exists as two splice variants, which vary by 20 amino acids. Defects in ATP2C1 cause Hailey-Hailey disease, which is an autosomal dominant disorder that is characterized by blisters and erosions of the skin. These findings provide further evidence that PMR1 plays a key role in maintaining the integrity of the epidermis by controlling intracellular calcium signaling. Applications: Western Bloting: 1:500-1:2000., Immunohistochemistry: 1:200-1:1000., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-ATP2C1, Anti-HUSSY-28, Anti-KIAA1347, Anti-ATPase 2C1, EC=3.6.3.8, Anti-ATP-dependent Ca(2+) pump PMR1, Anti-Calcium-transporting ATPase type 2C member 1
Supplier: United States Biological
Supplier-Nr: 029976

Properties

Application: ELISA, IHC, WB
Antibody Type: Monoclonal
Clone: 13B54
Conjugate: No
Host: Mouse
Reactivity: Human, Monkey
Immunogen: Purified recombinant fragment of ATP2C1 expressed in E. coli.

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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