Anti-Atg16L1

Anti-Atg16L1
Promotion:

Bethyl is giving away a free permanent marker for every Bethyl purchase until supplies last!

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A303-295A-T 10 µl (10 µg) -

3 - 9 business days

125.00€
A303-295A 100 µl (100 µg) -

3 - 9 business days

430.00€
 
Protein function: Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the... more
Product information "Anti-Atg16L1"
Protein function: Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane (PubMed:24553140, PubMed:23376921, PubMed:24954904, PubMed:27273576, PubMed:23392225). Regulates mitochondrial antiviral signaling (MAVS)-dependent type I interferon (IFN-I) production (PubMed:25645662). Negatively regulates NOD1- and NOD2- driven inflammatory cytokine response (PubMed:24238340). Plays a role in regulating morphology and function of Paneth cell (PubMed:18849966). [The UniProt Consortium]
Keywords: Anti-APG16L, Anti-ATG16L1, Anti-APG16-like 1, Anti-Autophagy-related protein 16-1
Supplier: Bethyl Laboratories
Supplier-Nr: A303-295A-T

Properties

Application: IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Orangutan)
Immunogen: synthetic peptide. The epitope recognized by A303-295A-T maps to a region between residue 300 and 350 of human ATG16 Autophagy Related 16-like 1 using the numbering given in entry NP_110430.5 (GeneID 55054).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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