Anti-Atg16L1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A303-295A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A303-295A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the... more

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Product information "Anti-Atg16L1"

Protein function: Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane (PubMed:24553140, PubMed:23376921, PubMed:24954904, PubMed:27273576, PubMed:23392225). Regulates mitochondrial antiviral signaling (MAVS)-dependent type I interferon (IFN-I) production (PubMed:25645662). Negatively regulates NOD1- and NOD2- driven inflammatory cytokine response (PubMed:24238340). Plays a role in regulating morphology and function of Paneth cell (PubMed:18849966). [The UniProt Consortium]

Keywords:	Anti-APG16L, Anti-ATG16L1, Anti-APG16-like 1, Anti-Autophagy-related protein 16-1
Supplier:	Bethyl Laboratories
Supplier-Nr:	A303-295A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: orangutan)
Immunogen:	synthetic peptide. The epitope recognized by A303-295A-T maps to a region between residue 300 and 350 of human ATG16 Autophagy Related 16-like 1 using the numbering given in entry NP_110430.5 (GeneID 55054).
Format:	Antigen Affinity Purified