Anti-ASH2L

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-14753.20 20 µl -

7 - 16 business days*

71.00€
E-AB-14753.60 60 µl -

7 - 16 business days*

143.00€
E-AB-14753.120 120 µl -

7 - 16 business days*

238.00€
E-AB-14753.200 200 µl -

7 - 16 business days*

396.00€
 
The human ASH2L gene encodes a 628 amino acid protein known as ASH2L1, or isoform 1, which... more
Product information "Anti-ASH2L"
The human ASH2L gene encodes a 628 amino acid protein known as ASH2L1, or isoform 1, which contains a nuclear localization signal and PHD finger motif, suggesting that the gene product functions as a transcription regulator. Alternative splicing results in a shorter isoform 2, designated ASH2L2, which is missing the first 94 amino acid residues found in ASH2L1. Human ASH2L proteins are 60% homologous to Drosophila ash2, which positively regulates expression of certain genes in early development, and contain similar, but not identical, domains, including a zinc finger motif. ASH2L is highly expressed in fetal liver, testis and leukemia cell lines with erythroid and megakaryocytic potential, such as K562, Hel and Dami. Protein function: Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis. [The UniProt Consortium]
Keywords: Anti-ASH2L, Anti-ASH2L1, Anti-ASH2-like protein, Anti-Set1/Ash2 histone methyltransferase complex subunit ASH2, ASH2L Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-14753

Properties

Application: IHC, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: Recombinant protein of human ASH2L
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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