Anti-ARRDC1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA044345.100	100 µl		-		3 - 8 business days*		491.00€

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Protein function: Functions as an adapter recruiting ubiquitin-protein ligases to their specific... more

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Product information "Anti-ARRDC1"

Protein function: Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates (PubMed:23886940, PubMed:27462458). Through an ubiquitination-dependent mechanism plays for instance a role in the incorporation of SLC11A2 into extracellular vesicles (PubMed:27462458). More generally, plays a role in the extracellular transport of proteins between cells through the release in the extracellular space of microvesicles (PubMed:22315426). By participating in the ITCH-mediated ubiquitination and subsequent degradation of NOTCH1, negatively regulates the NOTCH signaling pathway (PubMed:23886940). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 91% and to rat: 92%

Keywords:	Anti-Alpha-arrestin 1, Anti-Arrestin domain-containing protein 1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA044345

Properties

Application:	IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: IHTPRFSKDH KCSLVFYILS PLNLNSIPDI EQPNVASATK KFSYKLVKTG SVVLTASTDL RGYVVGQALQ LHADVE (ATA-APrEST75456)