Anti-ARNT

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA001759.25	25 µl		-		7 - 10 business days*		330.00€
ATA-HPA001759.100	100 µl		-		7 - 10 business days*		463.00€

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Protein function: Required for activity of the Ah (dioxin) receptor. This protein is required for... more

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Product information "Anti-ARNT"

Protein function: Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia. The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription (PubMed:28396409). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 82% and to rat: 83%

Keywords:	Anti-ARNT, Anti-BHLHE2, Anti-bHLHe2, Anti-HIF1-beta, Anti-HIF-1-beta, Anti-ARNT protein, Anti-Hypoxia-inducible factor 1-beta, Anti-Dioxin receptor, nuclear translocator, Anti-Class E basic helix-loop-helix protein 2
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA001759

Properties

Application:	ICC, IHC, ChIP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: RFSCLRPRVA GTTEMTSDVP SLGPAIASGN SGPGIQGGGA IVQRAIKRRP GLDFDDDGEG NSKFLRCDDD QMSNDKERFA RSDDEQSSAD KERLARENHS EIERRRRNKM TAYITELSDM V (ATA-APrEST84777)