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Expression of this gene is affected by vitamin A. The encoded protein of this gene may be associated with the cytoskeleton. A similar protein in rats may play a role in the regulation of cell differentiation. The rat protein binds and inhibits the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic acid, which results in a specific reduction in EAAC1-mediated glutamate transport. Protein function: Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate in a PKC activity- dependent manner. Plays a role in the retention of SLC1A1/EAAC1 in the endoplasmic reticulum. [The UniProt Consortium]
Keywords:
JM5, Aip-5, DERP11, ARL6IP5, HSPC127, GTRAP3-18, Protein JWa, PRA1 family protein 3, ARL-6-interacting protein 5, Dermal papilla-derived protein 11, Prenylated Rab acceptor protein 2, Putative MAPK-activating protein PM27, ARL6IP5 Polyclonal Antibody
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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