Anti-ARHGEF5

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA020980.25 25 µl -

3 - 8 business days*

369.00€
ATA-HPA020980.100 100 µl -

3 - 8 business days*

491.00€
 
Protein function: Guanine nucleotide exchange factor which activates Rho GTPases... more
Product information "Anti-ARHGEF5"
Protein function: Guanine nucleotide exchange factor which activates Rho GTPases (PubMed:15601624). Strongly activates RHOA (PubMed:15601624). Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1. Involved in regulation of cell shape and actin cytoskeletal organization (PubMed:15601624). Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia (PubMed:14662653). Required for SRC-induced podosome formation. Involved in positive regulation of immature dendritic cell migration. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 46% and to rat: 45%
Keywords: Anti-TIM, Anti-p60 TIM, Anti-ARHGEF5, Anti-Ephexin-3, Anti-Oncogene TIM, Anti-Rho guanine nucleotide exchange factor 5, Anti-Guanine nucleotide regulatory protein TIM, Anti-Transforming immortalized mammary oncogene
Supplier: Atlas Antibodies
Supplier-Nr: HPA020980

Properties

Application: ICC, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: PAREPLRRTT PQQGASGPGR SPVGQARQPE KPSHLHLEKA SSWPHRRDSG RPPGDSSGQA VAPSEGANKH KGWS (ATA-APrEST74862)

Database Information

KEGG ID : K20684 | Matching products
UniProt ID : Q12774 | Matching products
Gene ID : GeneID 7984 | Matching products
Protein Atlas Nr. : ENSG00000050327

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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