Anti-ARHGEF4, N-terminal

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG63690.100	100 µg		-	-	6 - 14 business days*		871.00€

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Protein function: Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42... more

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Product information "Anti-ARHGEF4, N-terminal"

Protein function: Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression. [The UniProt Consortium]

Keywords:	Anti-Asef, Anti-Asef1, Anti-ARHGEF4, Anti-KIAA1112, Anti-Rho guanine nucleotide exchange factor 4, Anti-APC-stimulated guanine nucleotide exchange factor 1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG63690

Properties

Application:	ELISA, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Goat
Species reactivity:	human
Immunogen:	PWEEPAGEKPSCS
Format:	Ammonium Sulfate Precipitated

Database Information

KEGG ID :	K05769 \| Matching products
UniProt ID :	Q9NR80 \| Matching products
Gene ID :	GeneID 50649 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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View product citations for antibody ARG63690 on CiteAb

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