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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG42367.100 | 100 µg | - | - |
6 - 14 business days* |
658.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42... more
Product information "Anti-ARHGEF4, clone ARHGEF-08"
Protein function: Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up- regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression. [The UniProt Consortium]
| Keywords: | Anti-Asef, Anti-Asef1, Anti-ARHGEF4, Anti-KIAA1112, Anti-Rho guanine nucleotide exchange factor 4, Anti-APC-stimulated guanine nucleotide exchange factor 1 |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG42367 |
Properties
| Application: | FC, WB |
| Antibody Type: | Monoclonal |
| Clone: | ARHGEF-08 |
| Conjugate: | No |
| Host: | Mouse |
| Species reactivity: | human |
| Immunogen: | Recombinant fragment corresponding to aa. 143-271 of Human ARHGEF4 |
| MW: | 79 kD |
| Format: | Purified |
Database Information
| KEGG ID : | K05769 | Matching products |
| UniProt ID : | Q9NR80 | Matching products |
| Gene ID : | GeneID 50649 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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