Anti-ARHGEF4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA018267.25	25 µl		-		7 - 10 business days*		246.00€
ATA-HPA018267.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42... more

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Product information "Anti-ARHGEF4"

Protein function: Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up- regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 89% and to rat: 89%

Keywords:	Anti-Asef, Anti-Asef1, Anti-ARHGEF4, Anti-KIAA1112, Anti-Rho guanine nucleotide exchange factor 4, Anti-APC-stimulated guanine nucleotide exchange factor 1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA018267

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: VLYYKGRLDM DGLEVVDLED GKDRDLHVSI KNAFRLHRGA TGDSHLLCTR KPEQKQRWLK AFAREREQVQ LDQETG (ATA-APrEST74641)