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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ELK-ES1696.50 | 50 µl | - | - |
10 - 14 business days* |
173.00€
|
||
| ELK-ES1696.100 | 100 µl | - | - |
10 - 14 business days* |
290.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
ARHGAP18 belongs to a family of Rho (see MIM 165390) GTPase-activating proteins that modulate... more
Product information "Anti-ARHGAP18"
ARHGAP18 belongs to a family of Rho (see MIM 165390) GTPase-activating proteins that modulate cell signaling (Potkin et al., 2009 [PubMed 19065146]).[supplied by OMIM, Apr 2010], Protein function: Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state (PubMed:21865595). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1 (PubMed:25778702). Regulates cell shape, spreading, and migration (PubMed:21865595). [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.. Cellular localization: Cytoplasm .
| Keywords: | Anti-MacGAP, Anti-Rho GTPase-activating protein 18, Anti-Rho-type GTPase-activating protein 18, ARHGAP18 rabbit pAb |
| Supplier: | ELK Biotechnology |
| Supplier-Nr: | ES1696 |
Properties
| Application: | WB, IHC, IF, ELISA |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, rat, mouse, |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human RHG18. AA range:517-566 |
| MW: | 75 kD |
| Format: | Antiserum |
Database Information
| KEGG ID : | K20639 | Matching products |
| UniProt ID : | Q8N392 | Matching products |
| Gene ID : | GeneID 93663 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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