Anti-ARHGAP18

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA031595.25	25 µl		-		7 - 10 business days*		246.00€
ATA-HPA031595.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: Rho GTPase activating protein that suppresses F-actin polymerization by... more

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Product information "Anti-ARHGAP18"

Protein function: Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state (PubMed:21865595). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1 (PubMed:25778702). Regulates cell shape, spreading, and migration (PubMed:21865595). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 79% and to rat: 78%

Keywords:	Anti-MacGAP, Anti-Rho GTPase-activating protein 18, Anti-Rho-type GTPase-activating protein 18
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA031595

Properties

Application:	ICC, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: STTIKVMEKP PFDRSISQDS LDELSMEDYW IELENIKKSS ENSQEDQEVV VVKEPDEGEL EEEWLKEAGL SNLFGESAGD PQESI (ATA-APrEST77615)