Anti-ARHGAP17

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A304-689A-T	10 µl (10 µg)		-		2 - 8 business days*		165.00€
A304-689A	100 µl (100 µg)		-		2 - 8 business days*		586.00€

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Protein function: Rho GTPase-activating protein involved in the maintenance of tight junction by... more

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Product information "Anti-ARHGAP17"

Protein function: Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca(2+)-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1. [The UniProt Consortium]

Keywords:	Anti-RICH1, Anti-RICH-1, Anti-MSTP066, Anti-ARHGAP17, Anti-Rho GTPase-activating protein 17, Anti-Rho-type GTPase-activating protein 17, Anti-RhoGAP interacting with CIP4 homologs protein 1
Supplier:	Bethyl Laboratories
Supplier-Nr:	A304-689A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: orangutan, rhesus monkey, gorilla, chimpanzee, crab-eating macaque, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A304-689A-T maps to a region between residue 757 to 625 of human Rho GTPase activating Protein 17 using the numbering given in entry NP_001006635.1 (GeneID 55114).
Format:	Antigen Affinity Purified