Anti-Aquaporin 3

Anti-Aquaporin 3 Antibody was purified by affinity chromatography. A BLAST analysis was used to suggest cross-reactivity with Aquaporin 3 from Human, Mouse, and Rat based on 100% homology with the immunizing sequence. Other species not yet tested. Cross-reactivity with Aquaporin 3 from other sources has not been determined. Channels and Transporters research. Protein function: Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism. [The UniProt Consortium]