Anti-APG4B

Anti-APG4B
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-15507.20 20 µl -

7 - 16 business days*

71.00€
E-AB-15507.60 60 µl -

7 - 16 business days*

143.00€
E-AB-15507.120 120 µl -

7 - 16 business days*

238.00€
E-AB-15507.200 200 µl -

7 - 16 business days*

396.00€
 
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed... more
Product information "Anti-APG4B"
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Protein function: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C- terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. [The UniProt Consortium]
Keywords: Anti-APG4B, Anti-ATG4B, Anti-hAPG4B, EC=3.4.22.-, Anti-Autophagin-1, Anti-Cysteine protease ATG4B, Anti-AUT-like 1 cysteine endopeptidase, Anti-Autophagy-related protein 4 homolog B, Anti-Autophagy-related cysteine endopeptidase 1, APG4B Polyclonal Antibo
Supplier: Elabscience
Supplier-Nr: E-AB-15507

Properties

Application: WB, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: Synthetic peptide of human APG4B
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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