Anti-ANKFY1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA024513.100	100 µl		-		3 - 8 business days*		491.00€

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Protein function: Proposed effector of Rab5. Binds to phosphatidylinositol 3- phosphate (PI(3)P).... more

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Product information "Anti-ANKFY1"

Protein function: Proposed effector of Rab5. Binds to phosphatidylinositol 3- phosphate (PI(3)P). Involved in homotypic early endosome fusion and to a lesser extent in heterotypic fusion of chlathrin-coated vesicles with early endosomes. Involved in macropinocytosis, the function is dependent on Rab5-GTP. Required for correct endosomal localization. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Regulates the subcellular localization of the retromer complex in a EHD1-dependent manner. Involved in endosome-to-Golgi transport and biosynthetic transport to late endosomes and lysosomes indicative for a regulation of retromer complex-mediated retrograde transport. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 93% and to rat: 94%

Keywords:	Anti-ANKHZN, Anti-Rank-5, Anti-ANKFY1, Anti-Rabankyrin-5, Anti-Ankyrin repeats hooked to a zinc finger motif, Anti-Ankyrin repeat and FYVE domain-containing protein 1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA024513

Properties

Application:	IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: YVFSQLLQCK QLDLELKDHE GSTALWLAVQ HITVSSDQSV NPFEDVPVVN GTSFDENSFA ARLIQRGSHT DAPDTATGNC LLQRAAGAGN EAAALFLATN (ATA-APrEST75931)