Anti-ANKFY1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A305-512A-T	10 µl (10 µg)		-		3 - 7 business days*		165.00€
A305-512A	100 µl (100 µg)		-		3 - 7 business days*		586.00€

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Protein function: Proposed effector of Rab5. Binds to phosphatidylinositol 3-phosphate (PI(3)P).... more

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Product information "Anti-ANKFY1"

Protein function: Proposed effector of Rab5. Binds to phosphatidylinositol 3-phosphate (PI(3)P). Involved in homotypic early endosome fusion and to a lesser extent in heterotypic fusion of chlathrin-coated vesicles with early endosomes. Involved in macropinocytosis, the function is dependent on Rab5-GTP. Required for correct endosomal localization. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Regulates the subcellular localization of the retromer complex in a EHD1- dependent manner. Involved in endosome-to-Golgi transport and biosynthetic transport to late endosomes and lysosomes indicative for a regulation of retromer complex-mediated retrograde transport. [The UniProt Consortium]

Keywords:	Anti-ANKFY1, Anti-Rank-5, Anti-ANKHZN, Anti-Rabankyrin-5, Anti-Ankyrin repeats hooked to a zinc finger motif, Anti-Ankyrin repeat and FYVE domain-containing protein 1
Supplier:	Bethyl Laboratories
Supplier-Nr:	A305-512A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	synthetic peptide. The epitope recognized by A305-512A-T maps to a region between residue 1 to 50 of human Ankyrin repeat and FYVE domain-containing protein 1 using the numbering given in entry Q9P2R3.2 (GeneID 51479).
Format:	Antigen Affinity Purified