Anti-Angiotensin Converting Enzyme-2, NT (ACE2, ACEH)

Anti-Angiotensin Converting Enzyme-2, NT (ACE2, ACEH)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A2295-01W6.100 100 µg - -

3 - 19 business days*

511.00€
 
Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial... more
Product information "Anti-Angiotensin Converting Enzyme-2, NT (ACE2, ACEH)"
Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology (1-2). In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. Recently. ACE2 has also been shown to be a functional receptor of the SARS coronavirus (3). The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function (4). Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.5-2ug/ml. Human kidney or human testis cell lysate can be used as positive control., Immunohistochemistry: 2ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-ACE2, EC=3.4.17.23, Anti-Metalloprotease MPROT15, Anti-ACE-related carboxypeptidase, Anti-Angiotensin-converting enzyme 2, Anti-Angiotensin-converting enzyme homolog, Anti-Processed angiotensin-converting enzyme 2
Supplier: United States Biological
Supplier-Nr: A2295-01W6

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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