Anti-Angiotensin Converting Enzyme 2, Ectodomain (ACE2, ACE-2, ACE-related Carboxypeptidase, Angiote

Anti-Angiotensin Converting Enzyme 2, Ectodomain (ACE2, ACE-2, ACE-related Carboxypeptidase, Angiote
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A2295-024.100 100 µg - -

3 - 19 business days*

692.00€
 
Angiogensin I Converting Enzyme-2 (ACE-2) is a type I transmembrane zinc protease that cleaves... more
Product information "Anti-Angiotensin Converting Enzyme 2, Ectodomain (ACE2, ACE-2, ACE-related Carboxypeptidase, Angiote"
Angiogensin I Converting Enzyme-2 (ACE-2) is a type I transmembrane zinc protease that cleaves angiotensins I and II to produce vasodilatory and anti-proliferative peptides. The balance between ACE-1 and ACE-2 activity is critical for maintaining cardiovascular, renal, and pulmonary function. ACE-2 isoforms of 75kD and 120kD are differentially expressed between lung and kidney, respectively, and a shed soluble form is generated by TACE/ADAM17 mediated cleavage. ACE-2 also functions as the cellular uptake receptor for the SARS coronoavirus. Within the extracellular domain, human ACE-2 shares 83% aa sequence identity with mouse and rat ACE-2. Applications: Suitable for use in ELISA, Western Blot, and Immunoprecipitation. Other applications not tested. Recommended Dilution: ELISA: 0.5-1.0ug/ml, Western Blot: 2ug/ml, Immunoprecipitation: 25ug/ml, Optimal dilutions to be determined by the researcher. Hybridoma: Mouse myeloma with B cells obtained from a mouse, Storage and Stability: Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: EC=3.4.17.23, Anti-Metalloprotease MPROT15, Anti-ACE-related carboxypeptidase, Anti-Angiotensin-converting enzyme 2, Anti-Angiotensin-converting enzyme homolog, Anti-Processed angiotensin-converting enzyme 2
Supplier: United States Biological
Supplier-Nr: A2295-024

Properties

Application: ELISA, IP, WB
Antibody Type: Monoclonal
Clone: 9H62
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: NS0-derived recombinant human ACE-2 ectodomain aa18-740, Q9BYF1.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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