Anti-Angiopoietin 2/ANG2 [R46-4B-1] Monoclonal Antibody,capture (PBS Only)

Angiopoietin 2/ANG2 Monoclonal Antibody,capture (PBS Only) from Assay Genie is a high quality antibody for research use only. Protein Function: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling (By similarity). Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1 (By similarity). In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression (By similarity). In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal (By similarity). Involved in the regulation of lymphangiogenesis (PubMed:28179430, PubMed:32908006) [The Uniprot Consortium]