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Protein function: Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions. [The UniProt Consortium]
synthetic peptide. The epitope recognized by A303-305A-T maps to a region between residue 1034 and 1084 of human Angiomotin using the numbering given in entry NP_001106962.1 (GeneID 154796).
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