Anti-ANFY1

Anti-ANFY1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES19574.50 50 µl - -

10 - 14 business days*

173.00€
ELK-ES19574.100 100 µl - -

10 - 14 business days*

290.00€
 
Protein function: Proposed effector of Rab5. Binds to phosphatidylinositol 3- phosphate (PI(3)P).... more
Product information "Anti-ANFY1"
Protein function: Proposed effector of Rab5. Binds to phosphatidylinositol 3- phosphate (PI(3)P). Involved in homotypic early endosome fusion and to a lesser extent in heterotypic fusion of chlathrin-coated vesicles with early endosomes. Involved in macropinocytosis, the function is dependent on Rab5-GTP. Required for correct endosomal localization. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Regulates the subcellular localization of the retromer complex in a EHD1-dependent manner. Involved in endosome-to-Golgi transport and biosynthetic transport to late endosomes and lysosomes indicative for a regulation of retromer complex-mediated retrograde transport. [The UniProt Consortium] Recommended dilutions: WB 1:1000-2000. Cellular localization: Cytoplasm . Endosome membrane , Peripheral membrane protein . Early endosome . Also associated with endosomal membranes. Localizes to macropinosomes. .
Keywords: Anti-ANKFY1, Anti-ANKHZN, Anti-Rank-5, Anti-Rabankyrin-5, Anti-Ankyrin repeats hooked to a zinc finger motif, Anti-Ankyrin repeat and FYVE domain-containing protein 1, ANFY1 rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES19574

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: Synthesized peptide derived from human ANFY1 AA range: 922-972
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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