Anti-Amylin

Amylin or islet amyloid polypeptide (IAPP) is produced in the pancreas beta cells and coreleased with insulin. The amino acid sequence shows great homology with CGRP. Amylin has been, shown to reverse insulin inhibition of hepatic gluconeogenesis and to inhibit muscle uptake of glucose. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry (Frozen and paraffin): 1:800-1:1500 Immunohistochemistry (PAP): 1:300-1:500 using FITC with overnight incubation at 4ºC., Optimal dilutions to be dtermined by the researcher. Positive Control: Formalin-fixed paraffin and frozen sections of human or rat pancreas. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.