Anti-AMER1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA065214.25	25 µl		-		3 - 8 business days*		246.00€
ATA-HPA065214.100	100 µl		-		3 - 8 business days*		491.00€

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Protein function: Regulator of the canonical Wnt signaling pathway. Acts by specifically binding... more

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Product information "Anti-AMER1"

Protein function: Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex. Acts both as a positive and negative regulator of the Wnt signaling pathway, depending on the context: acts as a positive regulator by promoting LRP6 phosphorylation. Also acts as a negative regulator by acting as a scaffold protein for the beta-catenin destruction complex and promoting stabilization of Axin at the cell membrane. Promotes CTNNB1 ubiquitination and degradation. Involved in kidney development. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 69% and to rat: 69%

Keywords:	Anti-AMER1, Anti-Amer1, Anti-FAM123B, Anti-Protein FAM123B, Anti-APC membrane recruitment protein 1, Anti-Wilms tumor gene on the X chromosome protein
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA065214

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: RDSPLSLYTE PPGAYDWPAW APCPLPVGPG PAWISPNQLD RPSSQSPYRQ ATCCIPPMTM SISLSVPESR APGESGPQLA RPSHLHLP (ATA-APrEST88770)