Anti-ALS2CR11

Anti-ALS2CR11
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES4905.50 50 µl - -

10 - 14 business days*

173.00€
ELK-ES4905.100 100 µl - -

10 - 14 business days*

290.00€
 
An autosomal recessive form of juvenile amyotrophic lateral sclerosis was originally mapped to a... more
Product information "Anti-ALS2CR11"
An autosomal recessive form of juvenile amyotrophic lateral sclerosis was originally mapped to a region of chromosome 2 that includes this gene. The encoded protein contains a calcium-dependent membrane targeting C2 domain. This domain is often found in proteins that are involved in membrane trafficking and signal transduction. [provided by RefSeq, Jun 2016], Protein function: Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for CatSper complex targeting and trafficking into the quadrilinear nanodomains. Targets the preassembled CatSper complexes to elongating flagella, where it links the channel- carrying vesicles and motor proteins. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.. Cellular localization:
Keywords: Anti-ALS2CR11, Anti-CatSper-tau, Anti-C2 calcium-dependent domain-containing protein 6, Anti-Cation channel sperm-associated targeting subunit tau, Anti-Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein, ALS2CR11 rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES4905

Properties

Application: WB, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, rat, mouse,
Immunogen: The antiserum was produced against synthesized peptide derived from human ALS2CR11. AA range:491-540
MW: 72 kD
Format: Antiserum

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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