Anti-alpha Actinin 4/ACTN4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A304-768A-T	10 µl (10 µg)		-		2 - 8 business days*		178.00€
A304-768A	100 µl (100 µg)		-		2 - 8 business days*		630.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: F-actin cross-linking protein which is thought to anchor actin to a variety of... more

Close menu

Product information "Anti-alpha Actinin 4/ACTN4"

Protein function: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (Probable). Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation (PubMed:15772161). Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions. May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA (PubMed:22351778). [The UniProt Consortium]

Keywords:	Anti-Alpha-actinin-4, Anti-Non-muscle alpha-actinin 4
Supplier:	Bethyl Laboratories
Supplier-Nr:	A304-768A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: rat, bovine)
Immunogen:	synthetic peptide. The epitope recognized by A304-768A-T maps to a region between residue 1 to 50 of human Alpha-actinin-4 using the numbering given in entry O43707 (GeneID 81).
Format:	Antigen Affinity Purified