Anti-alpha Actinin 4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG55162.100	100 µl		-	-	6 - 14 business days*		658.00€

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Protein function: F-actin cross-linking protein which is thought to anchor actin to a variety of... more

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Product information "Anti-alpha Actinin 4"

Protein function: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (Probable). Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation (PubMed:15772161). Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions. May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA (PubMed:22351778). [The UniProt Consortium]

Keywords:	Anti-Alpha-actinin-4, Anti-Non-muscle alpha-actinin 4
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG55162

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse, rat, bovine, chicken)
Immunogen:	KLH-conjugated synthetic peptide corresponding to aa. 192-220 (N-terminus) of Human alpha Actinin 4
Format:	Ammonium Sulfate Precipitated