Anti-Alpha-1-Antichymotrypsin / AACT / SERPINA3, clone AACT/1451

Anti-Alpha-1-Antichymotrypsin / AACT / SERPINA3, clone AACT/1451
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3227SAF-100UG 100 µg - -

3 - 10 business days

1 mg/ml in 1X PBS, BSA free, sodium azide free. Alpha 1-antichymotrypsin, or AACT, is a plasma... more
Product information "Anti-Alpha-1-Antichymotrypsin / AACT / SERPINA3, clone AACT/1451"
1 mg/ml in 1X PBS, BSA free, sodium azide free. Alpha 1-antichymotrypsin, or AACT, is a plasma protease inhibitor synthesized in the liver as a single glycopeptide chain. In human, the normal serum level of AACT is about one-tenth that of alpha 1-antitrypsin (AAT), with which it shares nucleic acid and protein sequence homology. Both are major acute phase reactants, their concentrations in plasma increase in response to trauma, surgery and infection. Elevated levels of AACT are widely, but not universally, reported in the cerebrospinal fluid and plasma of AD patients. Prostate-specific antigen (PSA) and its SDS-stable complex with AACT are in widespread use as markers for the diagnosis of prostate cancer. AACT deficiency may also be a possible cause of chronic liver disease. AACT antibody reacts with histiocytes and histiocytic neoplasms. It is widely used to identify histiocytes and tumors derived from them. Acinar tumors of the pancreas and salivary gland may also exhibit AACT positivity. Protein function: Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. [The UniProt Consortium]
Keywords: Anti-AACT, Anti-GIG24, Anti-SERPINA3, Alpha-1-Antichymotrypsin Antibody / AACT / SERPINA3
Supplier: NSJ Bioreagents
Supplier-Nr: V3227SAF-100UG


Application: WB, IHC (paraffin), FC, IF
Antibody Type: Monoclonal
Clone: AACT/1451
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: A human partial recombinant protein was used as the immunogen for this Alpha-1-Antichymotrypsin antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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