Anti-ALKBH8

Anti-ALKBH8
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-CAB7142.20 20 µl -

9 - 20 business days*

149.00€
 
Protein function: Catalyzes the methylation of 5-carboxymethyl uridine to 5- methylcarboxymethyl... more
Product information "Anti-ALKBH8"
Protein function: Catalyzes the methylation of 5-carboxymethyl uridine to 5- methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain (PubMed:20123966, PubMed:20308323, PubMed:31079898). Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA (PubMed:20123966, PubMed:20308323). Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys)(PubMed:20308323). Binds tRNA and catalyzes the iron and alpha-ketoglutarate dependent hydroxylation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its dioxygenase domain, giving rise to 5-(S)- methoxycarbonylhydroxymethyluridine, has a preference for tRNA(Gly) (PubMed:21285950). Required for normal survival after DNA damage (PubMed:20308323). May inhibit apoptosis and promote cell survival and angiogenesis (PubMed:19293182). [The UniProt Consortium]
Keywords: Anti-ABH8, Anti-ALKBH8, Anti-Alkylated DNA repair protein alkB homolog 8, Anti-Probable alpha-ketoglutarate-dependent dioxygenase ABH8, Anti-tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8
Supplier: Assay Genie
Supplier-Nr: CAB7142

Properties

Application: WB, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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