Anti-Alkaline Phosphatase / ALPL (tissue-nonspecific), clone V17.1

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V7411SAF-100UG 100 µg - -

3 - 10 business days*

752.00€
 
1 mg/ml in 1X PBS, BSA free, sodium azide free. There are at least four distinct but related... more
Product information "Anti-Alkaline Phosphatase / ALPL (tissue-nonspecific), clone V17.1"
1 mg/ml in 1X PBS, BSA free, sodium azide free. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization, however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. Protein function: This isozyme may play a role in skeletal mineralization. [The UniProt Consortium]
Keywords: Anti-ALPL, Anti-TNSALP, Anti-AP-TNAP, Anti-Alkaline phosphatase liver/bone/kidney isozyme, Anti-Alkaline phosphatase, tissue-nonspecific isozyme, Alkaline Phosphatase Antibody / ALPL (tissue-nonspecific)
Supplier: NSJ Bioreagents
Supplier-Nr: V7411SAF

Properties

Application: FC, IF, IHC (paraffin)
Antibody Type: Monoclonal
Clone: V17.1
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Alkaline Phosphatase
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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