Anti-AIF1 / Iba1 (Microglia Marker), clone MSVA-955M

Formulation: Purified Ab with BSA and Azide. Cellular Localization: Cell projection, Cytoplasm, Cytoskeleton, Phagocytic cup, Ruffle membrane. Positive Control: Colon: An at least moderate to strong cytoplasmic AIF1 immunostaining should be seen in mucosal macrophages. Chromosome Location: 6p21.33. Protein Function: Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation [The Uniprot Consortium]