Anti-AGO3 / Eif2c3

Anti-AGO3 / Eif2c3
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG45761.50 50 µg - -

6 - 14 business days*

501.00€
 
Protein function: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as... more
Product information "Anti-AGO3 / Eif2c3"
Protein function: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Proposed to be involved in stabilization of small RNA derivates (siRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent siRNA- dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4. Possesses RNA slicer activity but only on select RNAs bearing 5'- and 3'-flanking sequences to the region of guide-target complementarity (PubMed:29040713). [The UniProt Consortium]
Keywords: Anti-AGO3, Anti-hAgo3, Anti-hAgo3, Anti-EIF2C3, Anti-eIF2C 3, Anti-eIF2C 3, Anti-eIF-2C 3, Anti-eIF-2C 3, Anti-Argonaute3, Anti-Argonaute3, Anti-Protein argonaute-3, Anti-Protein argonaute-3, Anti-Argonaute RISC catalytic component 3, Anti-Argonaute RISC
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG45761

Properties

Application: FC, ICC, IF, IHC (paraffin), WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Recombinant protein containing to human AGO3 / Eif2c3
MW: 97 kD
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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