Anti-AFG3L2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA004480.25	25 µl		-		7 - 10 business days*		369.00€
ATA-HPA004480.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: ATP-dependent protease which is essential for axonal and neuron development. In... more

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Product information "Anti-AFG3L2"

Protein function: ATP-dependent protease which is essential for axonal and neuron development. In neurons, mediates degradation of SMDT1/EMRE before its assembly with the uniporter complex, limiting the availability of SMDT1/EMRE for MCU assembly and promoting efficient assembly of gatekeeper subunits with MCU (PubMed:27642048). Required for the maturation of paraplegin (SPG7) after its cleavage by mitochondrial-processing peptidase (MPP), converting it into a proteolytically active mature form. Required for the maturation of PINK1 into its 52kDa mature form after its cleavage by mitochondrial-processing peptidase (MPP) (PubMed:22354088). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 99% and to rat: 99%

Keywords:	Anti-AFG3-like protein 2, Anti-Paraplegin-like protein
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA004480

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: DKLARKLASL TPGFSGADVA NVCNEAALIA ARHLSDSINQ KHFEQAIERV IGGLEKKTQV LQPEEKKTVA YHEAGHAVAG WYLEHADPLL KVSIIPRGKG LGYAQYLPKE QYLYTKEQLL DRMCMTLGGR VSEEIFFGRI TTGAQDD (ATA-APrEST86846)