Anti-AF10 / MLLT10

Anti-AF10 / MLLT10
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-RQ8522 100 µg - -

7 - 12 business days*

790.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Protein AF-10 is a protein that in humans... more
Product information "Anti-AF10 / MLLT10"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Protein AF-10 is a protein that in humans is encoded by the MLLT10 gene. This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. Protein function: Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 'Lys-79' dimethylation (H3K79me2) and gene activation (PubMed:26439302). [The UniProt Consortium]
Keywords: Anti-Protein AF-10, Anti-ALL1-fused gene from chromosome 10 protein, AF10 Antibody / MLLT10, AF10 Antibody / MLLT10
Supplier: NSJ Bioreagents
Supplier-Nr: RQ8522

Properties

Application: WB, IF, FC, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: An E.coli-derived human recombinant protein (amino acids E541-S1068)
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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