Anti-Adropin

Adropin is a 76 amino acid secreted peptide expressed in the brain, liver, and plasma and is encoded by the energy homeostasis associated gene. It is very highly conserved in mammals, and is involved in glucose homeostasis and lipid metabolism. Plasma levels of adropin decrease with age and have been associated with metabolic disorders such as dyslipidemia and insulin resistance. Adropin is involved in post-transcriptional activation of eNOS, the up-regulation of VEGFR2, and activation of the ERK1/2 pathway. Adropin's involvement in endothelial cells results in increased proliferation and migration, and decreased permeability and apoptosis. Cayman's Adropin Polyclonal Antibody can be used for ELISA and Western blot applications. The antibody recognizes adropin at 14-17 kDa from human samples.Synonyms: Energy Homeostasis-Associated Protein. Immunogen: Thioredoxin fusion protein containing amino acids 34-76 of human adropin. Formulation: (Request formulation change), Protein-affinity purified IgG. Storage Buffer: TBS, pH 7.4, after resuspension in 500 µl of double distilled water. Host: Rabbit. Applications: ELISA and WB. UniProt Accession #: Q6UWT2.