Anti-ADA/Adenosine Deaminase

Anti-ADA/Adenosine Deaminase
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A305-182A-T 20 µl (2 blots) -

6 - 10 business days*

131.00€
A305-182A-M 100 µl (10 blots) -

6 - 10 business days*

313.00€
A305-182A 100 µl (100 µg) -

6 - 10 business days*

465.00€
 
Protein function: Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine... more
Product information "Anti-ADA/Adenosine Deaminase"
Protein function: Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine (PubMed:8452534, PubMed:16670267). Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4 (PubMed:20959412). Its interaction with DPP4 regulates lymphocyte- epithelial cell adhesion (PubMed:11772392). Enhances dendritic cell immunogenicity by affecting dendritic cell costimulatory molecule expression and cytokines and chemokines secretion. Enhances CD4+ T-cell differentiation and proliferation (PubMed:20959412). Acts as a positive modulator of adenosine receptors ADORA1 and ADORA2A, by enhancing their ligand affinity via conformational change (PubMed:23193172). Stimulates plasminogen activation (PubMed:15016824). Plays a role in male fertility (PubMed:21919946, PubMed:26166670). Plays a protective role in early postimplantation embryonic development. [The UniProt Consortium]
Keywords: Anti-ADA, Anti-ADA1, Anti-Adenosine deaminase, Anti-Adenosine aminohydrolase
Supplier: Bethyl Laboratories
Supplier-Nr: A305-182A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: synthetic peptide. The epitope recognized by A305-182A-T maps to a region between residue 1 to 50 of human Adenosine deaminase using the numbering given in entry P00813.3 (GeneID 100).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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