Anti-ACTH Cocktail, clone AH26 + 57

Anti-ACTH Cocktail, clone AH26 + 57
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3176SAF-100UG 100 µg - -

3 - 10 business days

541.00€
 
1 mg/ml in sterile PBS, BSA free, sodium azide free. ACTH (same as Corticotropin) is a 39 amino... more
Product information "Anti-ACTH Cocktail, clone AH26 + 57"
1 mg/ml in sterile PBS, BSA free, sodium azide free. ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This cocktail is specific to Synacthen (aa1-24 of ACTH), does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH. Protein function: ACTH stimulates the adrenal glands to release cortisol. [The UniProt Consortium]
Keywords: Anti-POMC, ACTH Antibody Cocktail
Supplier: NSJ Bioreagents
Supplier-Nr: V3176SAF-100UG

Properties

Application: FC, IF, IHC
Antibody Type: Mixed
Clone: AH26 + 57
Conjugate: No
Host: Mouse
Reactivity: Human, Mouse, Rat (Expected: Broad)
Immunogen: Amino acids 1-24 (AH26) and an N-terminal peptide from human ACTH (57) were used as the immunogens for this ACTH antibody cocktail.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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