Anti-ACP3 / Prostatic acid phosphatase, clone MSVA-452M

Antibody in 1X PBS with 0.05% BSA, 0.05% sodium azide. Prostatic acid phosphatase (ACP3), also known as PAP, is a secreted phosphatase highly expressed in prostate epithelium and widely used as a biomarker in prostate cancer research and pathology. Prostatic Acid Phosphatase Antibody for IHC (clone MSVA-452M) recognizes this prostate-associated enzyme, which belongs to the histidine acid phosphatase family and participates in phosphomonoester hydrolysis. PAP is predominantly expressed in prostate epithelial cells and secreted into prostatic fluid, where it contributes to normal prostate physiology and enzymatic activity within the gland.Prostatic Acid Phosphatase Antibody for IHC enables visualization of PAP protein expression in formalin-fixed paraffin-embedded tissues using immunohistochemistry. In IHC staining, PAP is typically detected in prostate epithelial cells where staining may appear cytoplasmic or luminal due to the secretory nature of the enzyme. This staining pattern reflects the physiological localization of prostatic acid phosphatase in glandular epithelial cells of the prostate and related secretory tissues.Immunohistochemistry detection of prostatic acid phosphatase has long been used in studies of prostate biology and prostate cancer. PAP expression is strongly associated with prostate epithelial differentiation and is frequently evaluated in prostate carcinoma research. IHC staining using Prostatic Acid Phosphatase Antibody for IHC allows researchers to identify PAP-positive prostate epithelial cells and examine expression patterns in prostate tumors and metastatic lesions.Prostatic acid phosphatase was historically used as one of the earliest biomarkers for prostate cancer prior to the introduction of PSA testing, and it continues to serve as a valuable marker of prostate epithelial differentiation. PAP expression can be observed in prostate glandular epithelium and prostate carcinoma cells, supporting studies of tumor differentiation and prostate tissue biology.Prostatic Acid Phosphatase Antibody for IHC provides a research tool for detecting PAP expression in prostate tissues and prostate cancer models. Immunohistochemistry staining of ACP3 enables investigators to examine prostate epithelial differentiation, evaluate tumor cell phenotype in prostate carcinoma, and study the biological role of ACP3 in prostate tissue physiology and prostate cancer progression.This ACP3 antibody is also part of a broader collection of IHC antibodies validated by tissue microarray analysis, supporting consistent staining across normal and cancer tissues.