Anti-ACOT8

Anti-ACOT8
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG59829.100 100 µl - -

10 - 15 business days*

707.00€
 
Protein function: Acyl-coenzyme A (acyl-CoA) thioesterases are a group of enzymes that catalyze... more
Product information "Anti-ACOT8"
Protein function: Acyl-coenzyme A (acyl-CoA) thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (PubMed:9299485, PubMed:9153233, PubMed:15194431). Acyl- coenzyme A thioesterase 8/ACOT8 display no strong substrate specificity with respect to the carboxylic acid moiety of Acyl- CoAs. Hydrolyzes medium length (C2 to C20) straight-chain, saturated and unsaturated acyl-CoAS but is inactive towards substrates with longer aliphatic chains (PubMed:9299485, PubMed:9153233). Moreover, it catalyzes the hydrolysis of CoA esters of bile acids, such as choloyl-CoA and chenodeoxycholoyl-CoA and competes with bile acid CoA:amino acid N-acyltransferase (BAAT). ACOT8 is also able to hydrolyze CoA esters of dicarboxylic acids. It is involved in the metabolic regulation of peroxisome proliferation (PubMed:15194431). [The UniProt Consortium]
Keywords: Anti-hTE, Anti-PTE-1, Anti-ACOT8, Anti-PTE-2, Anti-ACTEIII, Anti-hACTEIII, Anti-hACTE-III, Anti-Thioesterase II, Anti-Acyl-CoA thioesterase 8, Anti-Acyl-coenzyme A thioesterase 8, Anti-Choloyl-coenzyme A thioesterase
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG59829

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant fusion protein corresponding to aa. 1-220 of Human ACOT8 (NP_005460.2)
MW: 35 kD
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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