Anti-AcMNPV Major Envelope Glycoprotein Neutralizing Antibody (Clone M001)

Autographa californica multiple nucleopolyhedrovirus (AcMNPV) major envelope glycoprotein is a class III viral fusion protein. AcMNPV is a double-stranded DNA insect virus and member of the Baculoviridae family. AcMNPV major envelope glycoprotein exists as a trimer and is composed of five domains in the low pH, post-fusion state that is highly post-translationally modified via glycosylation sites and a palmitoylation site at the C-terminus. It is expressed on the surface of infected cells and budded virions. AcMNPV major envelope glycoprotein is involved in viral envelope-host cell endosome membrane fusion in a low pH-dependent manner and in virion budding. Lipoplexes containing AcMNPV major envelope glycoprotein have been used for gene delivery to mammalian cells, which can be inhibited by an AcMNPV major envelope glycoprotein neutralizing antibody. Cayman's AcMNPV Major Envelope Glycoprotein Neutralizing Antibody (Clone M001) can be used for microneutralization (MN) assays.Synonyms: AcMNPV GP64, Autographa californica Multicapsid Nucleopolyhedrovirus Major Envelope Glycoprotein, Autographa californica Multiple Nucleopolyhedrovirus Major Envelope Glycoprotein. Immunogen: Recombinant AcMNPV (strain E2). Clone Designation: M001. Formulation: (Request formulation change), 200 or 500 µg of protein A-affinity purified monoclonal antibody. Storage Buffer: 0.2 µm filtered solution in PBS. Host: Mouse. Isotype: IgG1. Applications: MN. Cross Reactivity: (+) Major envelope glycoprotein.