Anti-Acinus (Apoptotic Chromatin Condensation Inducer in the Nucleus, ACIN1, KIAA0670)

Apoptotic events such as chromatin condensation and nuclear fragmentation are triggered by the activation of a family of cysteine proteases called caspases.A novel protein, Acinus, induces apoptotic chromatin condensation after cleavage by caspase-3 without inducing DNA fragmentation and is essential for apoptotic chromatin condensation. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:1000, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.