Anti-ABCC3

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABS-KC-2367.50 50 µl - -

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206.00€
ABS-KC-2367.100 100 µl - -

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295.00€
 
Protein function: ATP-dependent transporter of the ATP-binding cassette (ABC) family that bind... more
Product information "Anti-ABCC3"
Protein function: ATP-dependent transporter of the ATP-binding cassette (ABC) family that bind and hydrolyze ATP to enable active transport of various substrates including many drugs, toxicants and endogenous compound across cell membranes (PubMed:11581266, PubMed:15083066, PubMed:10359813). Transports glucuronide conjugates such as bilirubin diglucuronide, estradiol-17-beta-o-glucuronide and GSH conjugates such as leukotriene C4 (LTC4) (PubMed:15083066, PubMed:11581266). Transports also various bile salts (taurocholate, glycocholate, taurochenodeoxycholate-3-sulfate, taurolithocholate- 3-sulfate). Does not contribute substantially to bile salt physiology but provides an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes. Can confers resistance to various anticancer drugs, methotrexate, tenoposide and etoposide, by decreasing accumulation of these drugs in cells (PubMed:11581266, PubMed:10359813). [The UniProt Consortium]
Keywords: Anti-ATP-binding cassette sub-family C member 3, Anti-Canalicular multispecific organic anion transporter 2, Anti-Multi-specific organic anion transporter D, Anti-MOAT-D, Anti-Multidrug resistance-associated protein 3, ABCC3 Antibody
Supplier: Absea
Supplier-Nr: KC-2367

Properties

Application: IHC
Antibody Type: Monoclonal
Clone: 16C3
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Recombinant human ABCC3
Format: Solution

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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