Anti-ABCC1

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA002380.25 25 µl -

7 - 10 business days*

300.00€
ATA-HPA002380.100 100 µl -

7 - 10 business days*

421.00€
 
Protein function: Mediates export of organic anions and drugs from the cytoplasm (PubMed:7961706,... more
Product information "Anti-ABCC1"
Protein function: Mediates export of organic anions and drugs from the cytoplasm (PubMed:7961706, PubMed:16230346, PubMed:9281595, PubMed:10064732, PubMed:11114332). Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17- beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics (PubMed:7961706, PubMed:16230346, PubMed:9281595, PubMed:10064732, PubMed:11114332). Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export (PubMed:9281595). Hydrolyzes ATP with low efficiency (PubMed:16230346). Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation (PubMed:17050692). Participates in inflammatory response by allowing export of leukotriene C4 from leukotriene C4-synthezing cells. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 76% and to rat: 73%
Keywords: Anti-MRP, Anti-LTC4 transporter, Anti-Leukotriene C(4) transporter, Anti-Multidrug resistance-associated protein 1, Anti-ATP-binding cassette sub-family C member 1, Anti-Glutathione-S-conjugate-translocating ATPase ABCC1
Supplier: Atlas Antibodies
Supplier-Nr: HPA002380

Properties

Application: ICC, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: LVTHSMSYLP QVDVIIVMSG GKISEMGSYQ ELLARDGAFA EFLRTYASTE QEQDAEENGV TGVSGPGKEA KQMENGMLVT DSAGKQLQRQ LSSSSSYSGD ISRHHNSTAE LQKAEAKKEE TWKLMEADKA QTGQVKLSVY WD (ATA-APrEST86067)

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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