AF/LE Purified Anti-Mouse NKG2A/C/E Antibody[20D5]

The NKG2 molecules are a family of lectin-like receptors that form heterodimers with CD94. NKG2/CD94 heterodimer are primarily expressed on NK cells, and a subset of CD8+ T cells. Studies of CD94/NKG2 heterodimers on NK cells have demonstrated that the NKG2 components transduce signals after ligand binding. NKG2A transduces inhibitory signals, while NKG2C and NKG2E transduce activating signals.