Products from Innaxon
Innaxon is a company based in Tewkesbury, United Kingdom focussing on innate immunity, Toll-like Receptor (TLR) agonists and small molecule inhibitors. Innaxon develops and manufactures defined “Immunoceuticals” of the highest activity and purity for pre-clinical research and development applications for vaccine adjuvants and immunotherapy. Their unique biological and synthetic TLR ligands are well-characterized and effective biological response modifiers of inappropriate or disproportionate immune responses.
More information at: www.adipogen.com/innaxon
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Lipid A from S. minnesota R595 (Re) TLRpure Sterile Solution
Item number: IAX-100-001-M001
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.1-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4), a member of the highly...
| Keywords: | Lipid A derived from S. minnesota strain R595 (Re) TLRpure LPS (biosynthetic) |
| Application: | TLR4 activator |
From 156.00€
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![Monophosphoryl Lipid A [MPLA] from S. minnesota R595 (Re) TLRpure Sterile Solution](https://www.biomol.com/media/image/67/fb/15/IAX-100-002-M001_200x200.png "Monophosphoryl Lipid A [MPLA] from S. minnesota R595 (Re) TLRpure Sterile Solution")
Monophosphoryl Lipid A [MPLA] from S. minnesota R595 (Re)...
Item number: IAX-100-002-C500
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.1-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4), a member of the highly...
| Keywords: | Monophosphoryl Lipid A [MPLA] derived from S. minnesota R595 (Re) TLRpure LPS (biosynthetic) |
| Application: | TLR4 activator |
From 211.00€
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LPS from S. abortus equi (S-form) Biotin TLRpure Sterile...
Item number: IAX-100-009B-C500
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.01-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
| Keywords: | Biotinylated Lipopolysaccharide (LPS) from S. abortus equi, S-type (smooth/wild-type) LPS |
| Application: | TLR4 activator |
From 184.00€
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LPS from E. coli EH100 (Ra) TLRpure Sterile Solution
Item number: IAX-100-010-C500
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.05-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
| Keywords: | Lipopolysaccharide (LPS) from E. coli strain EH100 (Ra), R-type (rough/mutant) LPS |
| Application: | TLR4 activator |
From 175.00€
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LPS from S. minnesota R60 (Ra) TLRpure Sterile Solution
Item number: IAX-100-016-C500
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.05-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
| Keywords: | Lipopolysaccharide (LPS) from S. minnesota strain R60 (Ra), R-type (rough/mutant) LPS |
| Application: | TLR4 activator |
From 197.00€
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LPS from S. minnesota R5 (Rc) TLRpure Sterile Solution
Item number: IAX-100-017-M001
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.05-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
| Keywords: | Lipopolysaccharide (LPS) from S. minnesota strain R5 (Rc), R-type (rough/mutant) LPS |
| Application: | TLR4 activator |
From 175.00€
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LPS from S. minnesota R3 (Rd2) TLRpure Sterile Solution
Item number: IAX-100-021-M001
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.05-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
| Keywords: | Lipopolysaccharide (LPS) from S. minnesota strain R3 (Rd2), R-type (rough/mutant) LPS |
| Application: | TLR4 activator |
From 175.00€
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Neutral-ODN (Control for iODNs) Endotoxin-free (sterile)
Item number: IAX-200-202-M001
Negative control GpC ODN for in vivo use in rodents (50-150 µg per injection). As active compound use CpG ODN 1585 (Cat. No.: IAX-200-003). For negative control without agonistic nor antagonistic activity: Neutral-ODN (Cat. No.: IAX-200-202).
| Application: | Negative Control for ODN 1585 (IAX-200-003) |
| MW: | 4821 D |
From 179.00€
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ODN 2243 (Control for ODN 2216) Endotoxin-free (sterile)
Item number: IAX-200-205-C100
Negative control GpC ODN for in vivo use in rodents (50-150 µg per injection). As active compound use CpG ODN 2216 (Cat. No.: IAX-200-005). For negative control without agonistic nor antagonistic activity: Neutral-ODN (Cat. No.: IAX-200-202).
| Application: | Negative Control for ODN 2216 (IAX-200-005) |
| MW: | 6684 D |
179.00€
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ODN 2137 (Control for ODN 2006) Endotoxin-free (sterile)
Item number: IAX-200-206-C100
Negative control GpC ODN for in vivo use in rodents (50-150 µg per injection). As active compound use CpG ODN 2006 (Cat. No.: IAX-200-006). For inegative control without agonistic nor antagonistic activity: Neutral-ODN (Cat. No.: IAX-200-202).
| Application: | Negative Control for ODN 2006 (IAX-200-006) |
| MW: | 6684 D |
179.00€
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IAXO-102 (CD14/TLR4 Antagonist) (synthetic)
Item number: IAX-600-002-M001
Described to interfere with human, rat and mouse TLR4/CD14 signaling, other species not tested. Optimal working concentration depends upon the type, purity and concentration and of TLR4 ligand, carrier protein such as LPS-binding protein (LBP), soluble and membrane-bound CD14, the presence of TLR4 co-receptors (e.g....
| Keywords: | Methyl 6-deoxy-6-amino-2,3-di-O-tetradecyl-?-D-glucopyranoside |
| Application: | CD14/TLR4 Antagonist |
| CAS | 1115270-63-7 |
| MW: | 585.94 D |
347.00€
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IAXO-103 (CD14/TLR4 Antagonist) (synthetic)
Item number: IAX-600-003-M001
Described to interfere with human, rat and mouse TLR4/CD14 signaling, other species not tested. Optimal working concentration depends upon the type, purity and concentration and of TLR4 ligand, carrier protein such as LPS-binding protein (LBP), soluble and membrane-bound CD14, the presence of TLR4 co-receptors (e.g....
| Keywords: | N-(3,4-bis-Tetradecyloxy-benzyl)-N-cyclopentyl-N,N-dimethylammonium iodide |
| Application: | CD14/TLR4 Antagonist |
| CAS | 1202208-36-3 |
| MW: | 755.98 D |
347.00€
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