Kataloge von Indigo Biosciences
INDIGlo Luciferase Detection Reagent
INDIGlo Luciferase Detection Reagent (LDR) is formulated to deliver steady, long-lived luminescence signal from mammalian reporter cells expressing firefly luciferase. The reagent is “ready to use”, without the requirement to first re-constitute powder-form components. INDIGlo LDR works equally well in quantifying expressed luciferase activity from 96-, 384-, or 1536-well format reporter assays. The resulting light emission is stable over a two-hour period with less than 10% fluctuation in signal, making INDIGlo LDR an ideal, economical detection reagent for both low- and high-throughput batch processing of assay plates. Released 2023.
Toxicology Assay Solutions
Do you know why labs choose and trust our partner Indigo Biosciences? They have the largest portfolio of nuclear receptor assays and their products enable researchers to achieve clear and reproducible results. The team at Indigo is commited to your study's success! Use this flyer to learn more about Indigo's toxicology assay solutions. Discover assay kits for hepatotoxicity, gene expression profiling and for human MDR1/P-Glycoprotein drug interaction. Additional in vitro toxicology and gene expression solutions are also available as screening services. Released 2023.
Environmental Monitoring
Environmental monitoring is important to be able to act quickly if toxic levels of chemicals are present in environmental samples. Harmful effects of endocrine disrupting chemicals (EDCs) and emerging contaminants affect organisms causing a wide range of developmental, reproductive, neurological, or metabolic defects in humans and wildlife. Indigo has an extensive list of cell-based bioassays that are predictive of cellular toxicity pathways including endocrine disruption, altered xenobiotic metabolism, and adaptive stress responses. Released 2023.
Cell-based Reporter Assays
The comprehensive portfolio of cell-based reporter assays manufactured by our partner Indigo Biosciences allows scientists to detect any biological activity that their test samples may exert against a specific receptor present in the cell. The assays utilize firefly luciferase reporter gene technology which provides superior precision and sensitivity. Since the receptor binding controls the expression of the luciferase reporter gene, luciferase activity in the cells can be correlated directly with the activity of the receptor. The strength of an interaction of a chemical with the target receptor is quantified using a luminometer to measure the level of light emitted. Released 2023.