Produkte von Indigo

Indigo

Indigo Biosciences, Inc. wurde im Jahr 2005 in State College, PA von Dr. Jack Vanden Heuvel und Dr. Blake Peterson gegründet. Das biowissenschaftliche Unternehmen konzentriert sich auf Produkte und Dienstleistungen im Bereich Kernrezeptoren, die eine wichtige Klasse von therapeutischen Wirkstoffzielen darstellen. Hierbei stellen quantitative Aktivitäts-Assays noch immer eine besondere Herausforderung für die Biotechnologie dar. Die beiden Gründer des Unternehmens sind international anerkannte Spezialisten auf diesem Gebiet und nutzten ihre gesammelte Expertise in der Kernrezeptorbiologie, Toxikologie, medizinischer Chemie und Molekularbiologie, um die Technologie-Plattform für diese Produkte zu entwickeln.

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PPARgamma (human) Reporter Assay Kit
PPARgamma (human) Reporter Assay Kit

Artikelnummer: IB-IB00102

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor gamma (NR1C3), a ligand-dependent transcription factor commonly referred to as PPARG or PPARgamma. INDIGO's reporter cells include the luciferase reporter gene functionally linked to a...
Anwendung: Functional activity screening
Reaktivität: Human
Format: Solid Phase
2.837,00 €
Bewerten
PPARalpha (human) Reporter Assay Kit
PPARalpha (human) Reporter Assay Kit

Artikelnummer: IB-IB00112

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor alpha (NR1C1), a ligand-dependent transcription factor commonly referred to as PPARA or PPARalpha. INDIGO's reporter cells include the luciferase reporter gene functionally linked to a...
Anwendung: Functional activity screening
Reaktivität: Human
Format: Solid Phase
2.837,00 €
Bewerten
PPARdelta (human) Reporter Assay Kit
PPARdelta (human) Reporter Assay Kit

Artikelnummer: IB-IB00122

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor delta (NR1C2), a ligand-dependent transcription factor commonly referred to as PPARD or PPARdelta. INDIGO's reporter cells include the luciferase reporter gene functionally linked to a...
Anwendung: Functional activity screening
Reaktivität: Human
Format: Solid Phase
2.837,00 €
Bewerten
PPAR (human) Reporter Assays Panel
PPAR (human) Reporter Assays Panel

Artikelnummer: IB-IB00131-32P

INDIGO's panel of PPAR reporter assays utilizes non-human mammalian cells engineered to express human peroxisome proliferator-activated receptors: PPARalpha (NR1C1), PPARdelta (NR1C2), or PPARgamma (NR1C3), all ligand-dependent transcription factors that are commonly referred to as PPARalpha, PPARdelta and PPARgamma. INDIGO's PPAR reporter cells include the luciferase...
Anwendung: Functional activity screening
Reaktivität: Human
Format: Solid Phase
1.422,00 €
Bewerten
GR (human) Reporter Assay Kit
GR (human) Reporter Assay Kit

Artikelnummer: IB-IB00202

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive high-level expression of full-length, unmodified human glucocorticoid receptor (NR3C1), a ligand-dependent transcription factor, commonly referred to as GR. INDIGO's reporter cells include the luciferase reporter gene functionally linked to a GR-responsive promoter....
Anwendung: Functional activity screening
Reaktivität: Human
Format: Solid Phase
2.837,00 €
Bewerten
LXRbeta (human) Reporter Assay Kit
LXRbeta (human) Reporter Assay Kit

Artikelnummer: IB-IB00302

This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of human liver X receptor beta (NR1H2), a ligand-dependent transcription factor commonly referred to as LXRbeta. INDIGO's reporter cells include the luciferase reporter gene functionally linked to a LXRbeta-responsive promoter. Thus,...
Anwendung: Functional activity screening
Reaktivität: Human
Format: Solid Phase
2.837,00 €
Bewerten
LXRalpha (human) Reporter Assay Kit
LXRalpha (human) Reporter Assay Kit

Artikelnummer: IB-IB00312

This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of human liver X receptor alpha (NR1H3), a ligand-dependent transcription factor commonly referred to as LXRalpha. INDIGO's reporter cells include the luciferase reporter gene functionally linked to a LXRalpha-responsive promoter. Thus,...
Anwendung: Functional activity screening
Reaktivität: Human
Format: Solid Phase
2.837,00 €
Bewerten
LXR (human) Reporter Assays Panel
LXR (human) Reporter Assays Panel

Artikelnummer: IB-IB00321-48P

INDIGO's panel of LXR Assays utilizes non-human mammalian cells engineered to express human estrogen receptors alpha (NR1H3) and beta (NR1H2), ligand-dependent transcription factors commonly referred to as LXRalpha and LXRbeta. INDIGO's reporter cells include the luciferase reporter gene functionally linked to an LXR-responsive promoter. Thus, quantifying changes in...
Anwendung: Functional activity screening
Reaktivität: Human
Format: Solid Phase
1.422,00 €
Bewerten
ERalpha (human) Reporter Assay Kit
ERalpha (human) Reporter Assay Kit

Artikelnummer: IB-IB00402

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the full-length human estrogen receptor 1 (NR3A1), a ligand-dependent transcription factor commonly referred to as ERalpha. INDIGO's reporter cells include the luciferase reporter gene functionally linked to an ERalpha-responsive promoter....
Anwendung: Functional activity screening
Reaktivität: Human
Format: Solid Phase
2.837,00 €
Bewerten
ERbeta (human) Reporter Assay Kit
ERbeta (human) Reporter Assay Kit

Artikelnummer: IB-IB00412

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the full-length human estrogen receptor 2 (NR3A2), a ligand-dependent transcription factor commonly referred to as ERbeta. INDIGO's reporter cells include the luciferase reporter gene functionally linked to a ERbeta-responsive promoter. Thus,...
Anwendung: Functional activity screening
Reaktivität: Human
Format: Solid Phase
2.837,00 €
Bewerten
ER (human) Reporter Assays Panel
ER (human) Reporter Assays Panel

Artikelnummer: IB-IB00421-48P

INDIGO's panel of ER assays utilizes non-human mammalian cells engineered to express human estrogen receptors alpha (ER1, NR3A1) and beta (ER2, NR3A2), ligand-dependent transcription factors commonly referred to as ERalpha and ERbeta. INDIGO's ER reporter cells include the luciferase reporter gene functionally linked to a responsive promoter. Thus, quantifying changes in...
Anwendung: Functional activity screening
Reaktivität: Human
Format: Solid Phase
1.422,00 €
Bewerten
MR (human) Reporter Assay Kit
MR (human) Reporter Assay Kit

Artikelnummer: IB-IB00502

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive high-level expression of full-length, unmodified human mineralocorticoid receptor (NR3C2), a ligand-dependent transcription factor commonly referred to as MR. INDIGO's reporter cells include the luciferase reporter gene functionally linked to a MR-responsive promoter....
Anwendung: Functional activity screening
Reaktivität: Human
Format: Solid Phase
2.837,00 €
Bewerten
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