Zytokine

In dieser Kategorie finden Sie Signalproteine und Peptide wie Interferone (IFN), Interleukine (IL), Koloniestimulierende Faktoren (CSF), Tumornekrosefaktoren (TNF), Chemokine sowie Wachstumsfaktoren. Zytokine regulieren die Differenzierung, Proliferation und Aktivität von Zellen und werden aus diesem Grund häufig in der Zellkultur eingesetzt. Eine weitere Funktion haben Zytokin-Produkte als Kontrollen in Immunassays. Informationen wie die spezifische Aktivität eines Zytokins, die Aminosäurensequenz, Ergebnisse eines Monozyten-Aktivierung-Tests und mehr finden Sie in den Datenblättern der Produkte.

In dieser Kategorie finden Sie Signalproteine und Peptide wie Interferone (IFN), Interleukine (IL), Koloniestimulierende Faktoren (CSF), Tumornekrosefaktoren (TNF), Chemokine sowie... mehr erfahren »
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Zytokine

In dieser Kategorie finden Sie Signalproteine und Peptide wie Interferone (IFN), Interleukine (IL), Koloniestimulierende Faktoren (CSF), Tumornekrosefaktoren (TNF), Chemokine sowie Wachstumsfaktoren. Zytokine regulieren die Differenzierung, Proliferation und Aktivität von Zellen und werden aus diesem Grund häufig in der Zellkultur eingesetzt. Eine weitere Funktion haben Zytokin-Produkte als Kontrollen in Immunassays. Informationen wie die spezifische Aktivität eines Zytokins, die Aminosäurensequenz, Ergebnisse eines Monozyten-Aktivierung-Tests und mehr finden Sie in den Datenblättern der Produkte.

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Tumor Necrosis Factor alpha (TNF alpha), human recombinant (HumaXpress)
Tumor Necrosis Factor alpha (TNF alpha), human...

Artikelnummer: HZ-1014

Authentic recombinant human protein, human cell expressed, which in general ensures proper folding, phosphorylation, disulfide bridge formation, proteolytic processing, and glycosylation. Endotoxin <0.1 EU/µg.
Anwendung: Cell culture, Bioassays
Wirt: Human cells
Reaktivität: Human
ab 99,00 €
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Interleukin-6 (IL-6), human recombinant (HumaXpress)
Interleukin-6 (IL-6), human recombinant...

Artikelnummer: HZ-1019

Authentic recombinant human protein, human cell expressed, which in general ensures proper folding, phosphorylation, disulfide bridge formation, proteolytic processing, and glycosylation. Endotoxin <0.5 EU/µg.
Anwendung: Cell culture, Bioassays
Wirt: Human cells
Reaktivität: Human
ab 195,00 €
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FasL (human) (multimeric) (rec., 3 x 10 µg MultiPack)
FasL (human) (multimeric) (rec., 3 x 10 µg...

Artikelnummer: AG-40B-0130-C010

(3 x 10 µg). Human FasL (aa 139-281) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG(R)-tag. Lyophilized. Contains PBS. MultimericFasL (human) is a high activity construct in which two trimeric FasL are artificially linked via the collagen domain of ACRP30. This construct very effectively simulates the natural membrane-assisted aggregation of FasL...
Anwendung: FasL aggregation stimulator
Wirt: Human cells
Reaktivität: Human, Mouse
MW: 40 kD
Format: Lyophilized
ab 363,00 €
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Insulin-Like Growth Factor-II, human recombinant (rHuIGF-2)
Insulin-Like Growth Factor-II, human...

Artikelnummer: 50342.50

The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 67 amino acids. The ED50 is less then 1.0 ng/ml, corresponding to a specific...
Anwendung: Cell culture
Wirt: E.coli
Reaktivität: Human
MW: 7505.00 D
ab 1,00 €
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Tumor Necrosis Factor alpha, human recombinant (rHuTNF-a)
Tumor Necrosis Factor alpha, human recombinant...

Artikelnummer: 50435.50

Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell...
Anwendung: Cell culture
Wirt: E.coli
Reaktivität: Human
MW: 17.5 kD
ab 1,00 €
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Interferon alpha1b, human recombinant (rHuIFN-alpha1b)
Interferon alpha1b, human recombinant...

Artikelnummer: 87390.20

Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain, 166 amino acids. The specific activity as determined in a viral resistance assay was found to be 1 x 108 IU/ mg.
Anwendung: Cell Culture
Wirt: E.coli
Reaktivität: Human
MW: 19392.00 D
Format: Lyophilized
ab 1,00 €
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IL-33 (oxidation resistant) (human) (rec.) (untagged)
IL-33 (oxidation resistant) (human) (rec.)...

Artikelnummer: AG-40B-0160-C100

Interleukin-33 (IL-33, HF-NEV, IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released upon cell lysis. IL-33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4 and TRAF6, followed by phosphorylation of ERK1 (MAPK3) / ERK2 (MAPK1),...
Anwendung: Cell culture, Binding assays
Wirt: E.coli
Reaktivität: Human
MW: 17 kD
Reinheit: >95%
Format: Purified
ab 264,00 €
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TGFbeta1, active human recombinant (rHuTGFbeta1)
TGFbeta1, active human recombinant (rHuTGFbeta1)

Artikelnummer: BPS-90900-2

Active human TGFb1 (GenBankAccession #NM_000660), a.a. 279-390(end), disulfide-linked homodimer. MW= approx. 25 kDa. Biological Activity: measured by TGFbeta1s ability to inhibit mIL-4-dependentproliferation of HT-2 mouse helper T cells.The ED50 is <0.05ng/ml.
Anwendung: Cell culture, Bioassays
Wirt: Human cells
Reaktivität: Human
MW: 25 kD
Reinheit: >95%
ab 114,00 €
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Interleukin-6 (IL-6), human recombinant (rHuIL-6)
Interleukin-6 (IL-6), human recombinant (rHuIL-6)

Artikelnummer: 009-001-310

Protein function: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig- secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells,...
Anwendung: Control/Immunoassays
Wirt: E.coli
Reaktivität: Human
MW: 21 kD
Format: Lyophilized
315,00 €
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Interleukin-3, human recombinant (rHuIL-3)
Interleukin-3, human recombinant (rHuIL-3)

Artikelnummer: 009-001-B92

Protein function: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. [The UniProt Consortium]
Anwendung: Control, Immunoassays
Wirt: E.coli
Reaktivität: Human
MW: 15,0 kD
Format: Lyophilized
315,00 €
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CD40L (human) (multimeric) (rec., 3 x 10 µg MultiPack)
CD40L (human) (multimeric) (rec., 3 x 10 µg...

Artikelnummer: AG-40B-0010-C010

(3 x 10 µg). Human CD40L (amino acids 116-261) is fused at the N-terminus to mouse ACRP30headless (amino acids 18-111) and a FLAG(R)-tag. Induces B cells activation (as demonstrated by dose-dependent upregulation of CD86) (ED50: <1ng/ml). Lyophilized. Contains PBS MultimericCD40L is a high activity construct in which two trimeric CD40 ligands are artificially linked via the...
Anwendung: Bioassays
Wirt: Hamster cells
Reaktivität: Human
Format: Lyophilized
ab 330,00 €
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BAFF (60-mer), Soluble (human, rec.), highly active (3 x 10 µg)
BAFF (60-mer), Soluble (human, rec.), highly...

Artikelnummer: AG-40B-0112-C010

Human BAFF (amino acids 134-285) is fused at the N-terminus to a His-tag. Lyophilized. Binds to human and mouse BAFF-R, TACI and BCMA. Relative binding affinity (EC50) for BAFF-R (human): 3ng/ml. Increases B cell survival /Proliferation. Increases CD21 / CD23 expression on B cells in vivo. Activates BAFF-R, TACI and BCMA receptors. Works at concentrations <20ng/ml.
Anwendung: Bioassays
Wirt: E.coli
Reaktivität: Human, Mouse
Format: Lyophilized
ab 220,00 €
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